Suppression of antibiotic resistance in multidrug-resistant Klebsiella pneumonia : The synergistic effect between antibiotics and essential oils of Thymus vulgaris and Origanum compactum

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Date

2024-09-23

Journal Title

Journal ISSN

Volume Title

Publisher

Université Mouloud Mammeri

Abstract

The growing problem of multidrug-resistant bacteria poses a serious public health challenge. This study explores the potential of natural compounds, specifically essential oils, as alternatives to fight resistant pathogens. By analyzing a multidrug-resistant strain of Klebsiella pneumoniae from a urinary infection, we assessed the antimicrobial effects of thyme (Thymus vulgaris) and oregano (Origanum compactum) essential oils. Both oils showed strong antibacterial activity through standard testing methods, suggesting their promise as alternatives to conventional antibiotics. Additionally, combining these essential oils with traditional antibiotics indicated a potential synergistic effect, improving antibiotic effectiveness and addressing resistance. This research supports the use of essential oils as complementary treatments to help control infections amid the rising threat of antibiotic resistance.

Description

81 p. : ill. ; 30 cm. (+ CD-Rom)

Keywords

Antibiotic resistance, Klebsiella pneumoniae, Essential oils, Thymus vulgaris, Origanum compactum, Synergy

Citation

Option : Microbial Biotechnology