Diamine Oxidase use as an anti-inflammatory dietary supplement

dc.contributor.authorArib, Lynda
dc.contributor.authorKaci, Azedine
dc.date.accessioned2022-12-14T12:56:52Z
dc.date.available2022-12-14T12:56:52Z
dc.date.issued2021
dc.description49 p. : ill. ; 30 cm. (+ CD-Rom)en
dc.description.abstractHistamine intolerance (HIT) has beenthe subjectofmany scientific studiesand is thought to be caused by a reduced intestinal degradation of this amine. The enzyme diamine oxidase (DAO) is considered for the gastrointestinal degradation of histamine. Histamine is an essential mediator of the pathophysiology of many allergic diseases. The inflammatory response is one of the effects exerted by histamine through its different receptors (H1, H2, H3, H4). The aim of this bibliographic review was to assess the efficacy of a new approach by implementing DAO enzyme as food supplementation in a preventive treatment for patients diagnosed with histamine intolerance. First we focused on reviewing the main sources of DAO (bacterial, vegetal and animal), discussing the process of extraction from known sources such as L. sativus and Porcine Kidney, and purification of plant and animal based DAO. We then reviewed and discussed the anti-inflammatory properties of the enzyme, which showed a significant reduction of every HIT-related symptom and its intensity due to DAO oral supplements.en
dc.identifier.citationOption : Nutritional Biochemistryen
dc.identifier.urihttps://dspace.ummto.dz/handle/ummto/18918
dc.language.isoenen
dc.publisherUniversité Mouloud Mammerien
dc.subjectDAOen
dc.subjectHistamineen
dc.subjectAmine oxidasesen
dc.subjectInflammatory responseen
dc.subjectHistamine intoleranceen
dc.subjectOral supplementsen
dc.titleDiamine Oxidase use as an anti-inflammatory dietary supplementen
dc.typeThesisen

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